Welcome to California Research Institute

At California Research Institute, we are dedicated to advancing medical knowledge and improving patient care through clinical research. Below, you'll find information about our currently enrolling studies. If you or someone you know is interested in participating, please contact us for more details.

We are currently enrolling for the following clinical research studies:

Non-Oncology

Study 1: Systemic Lupus Erythematosus (SLE)

This study evaluates the long-term safety and efficacy of XXXXXX in adult participants with active systemic lupus erythematosus.

Study 2: Rheumatoid Arthritis (RA)

This study aims to evaluate the efficacy and safety of XXXXXX in patients with rheumatoid arthritis. The trial is designed to provide real-world evidence on the effectiveness of XXXXX in managing symptoms and improving the quality of life for patients with rheumatoid arthritis.

Study 3: Chronic Obstructive Pulmonary Disease (COPD)

This study aims to evaluate the long-term safety and tolerability of XXXXX in patients with chronic obstructive pulmonary disease (COPD) who have previously participated in either the XXXXXX or XXXXXXX clinical studies. The trial is designed to provide comprehensive data on the continued use of Itepekimab for managing COPD symptoms and improving patient outcomes.

Study 4: Thyroid Eye Disease (TED)

This study aims to evaluate the efficacy and safety of XXXXX for the treatment of participants with active thyroid eye disease (TED). The trial is designed as a multi-center, randomized, quadruple-masked, placebo-controlled study to provide robust data on the effectiveness of XXXXXXX in managing TED symptoms and improving patient outcomes.

Study 5: Pediatric Iron Deficiency Anemia

This study aims to evaluate the efficacy and safety of XXXXX XXXXXXXXXXX in children aged 0 to <18 years with iron deficiency anemia due to non-dialysis-dependent chronic kidney disease (NDD-CKD) or with iron deficiency anemia who are intolerant or unresponsive to oral XXXXXXX. The trial is designed as a prospective, open-label, multi-center study to provide comprehensive data on the effectiveness of XXXX XXXXXXXXXX in managing iron deficiency anemia in these populations.

Study 6: Bone Mineral Density (BMD)

This study aims to evaluate the efficacy and safety of the XXXXX or XXXXXXX (XXX) tablet (USA only) in female subjects aged 14 to 45 years who are postmenarcheal for at least two years and premenopausal. Participants who choose to take the trial medication will be compared to those who choose to use non-hormonal contraceptive methods. The study will enroll participants into two cohorts: adolescents aged 14-17 (Cohort 1) and adults aged 18-45 (Cohort 2). Please note: Cohort 2 is currently closed.

Oncology

Study 1: Breast Cancer

This study aims to compare the efficacy and safety of XXXXX-XXXX versus XXXXXX in treating estrogen receptor-positive, HER2-negative advanced breast cancer. This is for patients whose disease has progressed after prior endocrine-based treatment.

Study 2: Solid Tumors

This study evaluates the safety, tolerability, pharmacokinetics, pharmacodynamics, and efficacy of XXXX-XXX alone and in combination with XXXXXXX in subjects with advanced MTAP-null solid tumors.

Study 3: Prostate Cancer

This study evaluates the efficacy and safety of XXXXX in combination with XXXXX compared to XXXXXXX-XXXX alone in treating subjects with metastatic castration-resistant prostate cancer (mCRPC).

Study 4: Non-Small Cell Lung Cancer

This study is for patients with advanced/metastatic non-small cell lung cancer (NSCLC) who have not received any treatment through the vein for the advanced disease

Please note: These oncology studies do not represent all studies currently enrolling at our site. Contact us for a complete list of current studies.

For more information about our clinical trials or to see if you qualify for participation, please contact us today.